September 2020

We are pleased to announce the addition of residue trials on honey to our pollinator studies portfolio

Our team specialised on pollinator studies is still busy conducting residue trials and effect-studies on honey bees (Apis mellifera L.), solitary bees (Osmia sp.) or bumble bees (Bombus terrestris) under semi-field and field
conditions in Central and South Europe.

We have some space available for the full range of field and semi-field studies commencing in the next year. extract from our diverse Ecotox-studies portfolio:

  • Honey bee standard studies according to OEPP/EPPO Guideline No. 170
  • Honey bee brood semi-field studies according OECD  guidance document no. 75
  • Bumble bee semi-field and field studies
  • Solitary bee semi-field and field studies according to ICPPR Ring test protocol, 2020
  • studies for special requests

Diverse matrix samplings (e.g. for residue analysis or health control) can be included in all study types.

We are experts in pollinator testing...!

July 2020

New Job offer: Assistenz der Geschäftsleitung (m/w/d)


More information ...

June 2020

Why you should use video to supplement study reports?


Amanda Prosser makes great videos to support our wildlife field studies.

Take a look at her new video:

June 2020

Expansion of our Regulatory services


tier3 solutions is happy to announce further expansion of our Regulatory services - in particular:




 With our new expert collaboration of extera and tier3 solutions, you will find competent support for:

  • Testing strategies and monitoring of Toxicology, Metabolism and Dermal Absoption studies
  • Non-Dietary Human Exposure Assessment
  • Dossier preparation for active substances (Doc M-CA section 5, M-CP section 7) and products (dRR Part B section 3)
  • Technical Equivalence of active substances (Tier I+II)

Please find further details here:


May 2020

Expansion of the Regulatory team


tier3 solutions is happy to announce further expansion of our regulatory expertise - in particular: Phys-chem properties, analytical methods and consumer safety.


Miriam Houtermans joined out team on May 1st, being located in Berlin.


Miriam brings in more than three years of experince in regulatory affairs of plantv production products in the EU. As an agricultural engineer, with PhD in soil science at the institute of crop science and resource conservation (University of Bonn), she has an outstanding knowledge about agriculture.


Miriam is an expert in project management, coordination and dossier preparation for crop protection actives and products (AIR, dRR, MRL, JMPR, LEX, IT), data gap analysis and monitoring of GLP studies, especially regarding the analytical methods and consumer safety (residue) sections.


At tier3 solutions, she will build up and expand analytical methods and consumer safety section. Miriam is also part of the business development team.


 We welcome Miriam and wish her a very good start.



May 2020


Our posters and presentations at

SETAC Europe 30th Annual Meeting,
03. – 07.05.2020, Dublin (Ireland), Online Meeting


Bat poster, SETAC 2020 tier3.pdf
Adobe Acrobat Dokument 1.4 MB
Focal species for pesticide RA, SETAC 20
Adobe Acrobat Dokument 1.8 MB
Food preferences of wood mice, SETAC 202
Adobe Acrobat Dokument 2.1 MB

Long-term effects on Common vole, SETAC
Adobe Acrobat Dokument 1.9 MB
New methods for lagomorph field studies,
Adobe Acrobat Dokument 2.9 MB
Use of video recording, SETAC 2020 tier3
Adobe Acrobat Dokument 1.3 MB

Christl et al 2020 Based on field data,
Adobe Acrobat Dokument 1.8 MB

March 2020

tier3 and the SARS-CoV-2/Covid-19 pandemic

Dear All,
The world and we all are facing challenging times due to the SARS-CoV-2/Covid-19 pandemic. The situation is changing every day.

However, we do assure you that we are still working at a normal level, and that we are doing our best to maintain public health - while retaining our usual high quality and efficiency.
Almost all staff members have started working from home and we have intensified our in-house hygienic procedures and personal precautions in accordance with public guidance. We do not receive any visitors and keep business travels to an absolute minimum, and also refrain from using public transport. So far, we do not have anybody in the company in quarantine, let alone infected.
This is a highly dynamic situation and no one can predict the development over the coming weeks and months. Our uppermost goal is to keep our staff and their contacts safe, but also to continue working in the best possible way. We are fully committed to you and your projects, and we will keep you updated about further developments.

If you have any questions, please do not hesitate to contact us anytime at or via your known personal contacts.

Stay healthy and kind regards,
Christian Wolf and Torsten Hauck

March 2020

Expansion of the Regulatory team


tier3 solutions is happy to announce the further expansion of our Regulatory team - in particular: the Environmental Fate team.

Dennis Wallace will join our tier3 team from March 1st on, being located at our office in Ludwigshafen. Dennis brings in about 5 years of professional experience as a study director in an E-Fate laboratory (DLR Agroscience, Germany). In future, he will take care of our contacts to E-Fate laboratories including study monitoring. In addition, he will be responsible for report writing and compilation of corresponding dossier chapters for the European registration of PPP´s. Furthermore, he will be involved in the Environmental Risk Assessment for active substances and products.

We welcome Dennis and wish him a very good start.


Oktober 2019

New branch office in Ludwigshafen am Rhein – Germany

To optimise our services for clients based in the Rhine-Main-Neckar region and in the southern parts of Germany as well as in Switzerland we open in October 2019 a branch office in Ludwigshafen am Rhein, located at the ‘Technologiezentrum Ludwigshafen’ (TZL)This facility is not only providing office space but also meeting and conference facilities for discussions with clients and workshops

Branch office Ludwigshafen: Donnersbergweg 1 | 67059 Ludwigshafen am Rhein

Torsten Hauck joins the board of tier3 as Managing Director

Effective on October 1st 2019 Torsten Hauck has joined the board of tier3 solutions GmbH as managing director. He will encompass the areas of business development, administration and especially the expansion of the regulatory affairs group with his expertise. For sure Christian Wolf will keep his role as managing director and will focus on the test facility, further developments of field studies and the regulatory science business.

June 2019

Our posters and presentations at

SETAC Europe 29th Annual Meeting,
26. – 30.05.2019, Helsinki (Finland)

nest monitoring standardisation designs
SETAC2019_tier3_Dittrich et al_ nest mon
Adobe Acrobat Dokument 1.2 MB
MDD vole
SETAC2019_tier3_Hotopp+Fuelling_MDD vole
Adobe Acrobat Dokument 989.6 KB
birds mammals field studies
SETAC2019_tier3_Fuelling et al_birds mam
Adobe Acrobat Dokument 1.6 MB

Long term PT approach
SETAC2019_tier3_Dittrich et al_Long term
Adobe Acrobat Dokument 955.1 KB
guttation exposure route
SETAC2019_tier3_Zumkier et al_guttation
Adobe Acrobat Dokument 442.8 KB
Bird home range variation
SETAC2019_tier3_Benito et al_Bird home r
Adobe Acrobat Dokument 2.0 MB

Rabbit field effects UK
SETAC2019_tier3_Fuelling et al_Rabbit fi
Adobe Acrobat Dokument 1.7 MB
Nest monitoring
SETAC2019_tier3_Russ et al_Nest monitori
Adobe Acrobat Dokument 1.3 MB

March 2019

Compendium of all published posters about field studies with Chlorpyrifos

February 2019

New publication of the tier3 team!


Dittrich R, Giessing B, Benito M Maria, Russ A, Wolf C, Foudoulakis M, Norman S (2019): Multiyear Monitoring of Bird Communities in Chlorpyrifos-Treated Orchards in Spain and the United Kingdom: Spatial and Temporal Trends in Species Composition, Abundance, and Site Fidelity, Environmental Toxicology and Chemistry, Vol. 38, No. 3, January 2019, Pages 616-629

Multiyear Monitoring of Bird Communities
Adobe Acrobat Dokument 1.7 MB

January 2019


MRLs in honey (SANTE/11956/2016 rev. 9):

tier3 solutions GmbH expanding honeybee services to Food and Dietary Safety



Honey has been considered as a food of animal origin (Annex I of Regulation 396/2005)and therefore, determination of the magnitude of pesticide residues and subsequent setting of maximum residues level (MRLs) in honey has to be considered in EU risk assessments.



Responding to the high demand for these MRL trials following the technical guideline published 14 Sep 2018, tier3 solutions GmbH has expanded its honeybee services. We offer semi-field studies for determining maximum residue levels (MRLs) in honey according to SANTE/11956/2016 rev. 9 in the central and the southern regulatory zone.



Our portfolio of testing and expertise is constantly growing. If you are interested in residue studies of other bee products or bee relevant matrices, contact us to discuss your requirements. We will find your solution.

tier3 solutions Workshop

"From the field to the risk assessment"



On 18th September the tier3 solutions workshop „from the field to the risk assessment“ with more than 40 participants from European regulatory authorities, Industry and CROs took place at the tier3 premises in Leverkusen.


The entire higher tier tool box of field study types was presented, including practical demonstrations, and the adequate design and evaluation of generic studies (Focal species, PT/PD), residue trials and field effects studies was vividly discussed.

Participants exchanged opinions and experiences and looked at the way forward for refined birds and mammals risk assessments and the importance of realistic data from sound field trials.

Emphasized were also useful statistical tools and how to present complex study results in ‚digestible‘ reports ‘ready to use’ in the regulatory process.


We thank all participants for a very interesting and productive day!


Our presented posters at


Setac Europe - 28th Annual Meeting,
13. – 17.05.2018, Rome (Italy)

Optimising design and analysis of acute effect field studies
Vertebrate risks assessments of a plant protection product (PPP) may indicate ...
Poster presentation Ralf Dittrich.pdf
Adobe Acrobat Dokument 882.9 KB
Field-effect studies as a suitable method to assess effects of plant protection products on free-living common voles (Microtus arvalis): A case study with the fungicide iprodione
After foliar spray application of a plant protection product on crops, food sources of ...
Poster presentation Olaf Fülling.pdf
Adobe Acrobat Dokument 1.6 MB
NTTPs – vegetative vs. reproductive endpoints - Is the potential increase in protectivity an indication of sensitivity or of relevance? (modelled vs. real data)
Herbicides are currently assessed for effects on non- target terrestrial plants (NTTP) by testing ...
Poster presentation Heino Christl.pdf
Adobe Acrobat Dokument 855.2 KB

tier3 solutions GmbH

Headquarter: Kolberger Str. 61-63 | 51381 Leverkusen | Germany

Branch office Ludwigshafen: Donnersbergweg 1 | 67059 Ludwigshafen am Rhein


Phone: +49 2171 55 997 0 | Fax: +49 2171 55 997 69 | E-mail: info|at|

Managing Directors: Dr. Christian Wolf & Torsten Hauck

Trade Register: Cologne HRB 70506 | VAT-No. DE 274 359 609